Everyone just assumes she'll inherit Wood Release- she doesn't.
She taught her assistant Shizune basic medical ninja skills, but she also became mentor to both Sakura Haruno and Ino Yamanaka.
We are told that the sons of the Sage fought over the inheritance of the clan right? In this headcanon I am imagining Konoha is closer to the one portrayed in Born Weapons.
After battling him and surviving, the three shinobi went their separate ways.
The way Mito's and Hashirama's relationship is introduced reminds me of how wifes are offered to powerful leaders from other families and nations seeking to strengthen relationships and alliances.
Those with that particular blood type are said to be passionate and creative.